FYI - I've tried the pay and support version of Wine called Crossover - available at https://www.codeweavers.com/store. It's $40 for the first year and $30/year after that, but it was a breeze to install Epanet on my El Capitan mac (10.11.4). I just pointed it to the downloaded official windows installer, and off it went.
Just thought to mention this since, even though its a pay option, I have found Wine to be very confusing, made so much more so by my natural reluctance to actually dig in and figure out how to use it just to run Epanet.
So far all seems to work flawlessly - more so I'd say than the previous version that broke at El Cap, which was always giving me trouble with popup window behavior.